News

Universal CAR T cells targeted to HER2 with a biotin-trastuzumab soluble linker penetrate spheroids and large tumor xenografts that are inherently resistant to trastuzumab mediated ADCC

The results of the research conducted by Lőrinc Nagy, Marianna Mezősi-Csaplár, István Rebenku, György Vereb, and Árpád Szöőr help to describe more accurately the mechanisms of new types of gene-modified immune cell-based targeted cancer therapies.

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Vivien Jusztus, Péter Hajdu and their colleagues in collaboration with the Department of Obstetrics and Gynecology of University of Debrecen studied the activity of potassium channels in CD8+ T lymphocytes.

Commemoration of 1848-1849

The University of Debrecen held a commemoration ceremony to mark the 176th anniversary of the 1848/49 Revolution and War of Independence. In keeping with tradition, the most outstanding members of the university's staff were also honoured this year.

The Research Group of Professor György Vereb

One of the most significant scientific achievements of recent years is the recommendation of researchers from the University of Debrecen in one of the world's leading oncology journals, Nature Reviews Clinical Oncology.

Dr Florina Zákány, a young researcher at the University of Debrecen, is working on developing a treatment to stop the death of nerve cells and alter the course of the disease

Florina Zákány, a young researcher at the University of Debrecen, is working to stop the process that leads to the death of nerve cells

Molecular rearrangements in S6 during slow inactivation in Shaker-IR potassium channels

Molecular rearrangements in S6 during slow inactivation in Shaker-IR potassium channels

A hét új káliumcsatorna-gátló peptid közül a CboK7 pikomoláris affinitással gátolja a Kv1.2-t.

Of seven new potassium channel inhibitor peptides, CboK7 inhibits Kv1.2 with picomolar affinity

HLA DQ protein changes the cell surface distribution pattern of HLA proteins as monitored by Förster resonance energy transfer and high-resolution electron microscopy

HLA DQ protein changes the cell surface distribution pattern of HLA proteins as monitored by Förster resonance energy transfer and high-resolution electron microscopy

Effects of the membrane lipid environment on the efficiency of cell-penetrating peptides

CD28 and 41BB costimulatory domains alone or in combination differentially influence cell surface dynamics and organization of chimeric antigen receptors and early activation of CAR T cells